Mark Rogge, Ph.D.

Adjunct Professor

Department: Pharmaceutics

Business Phone: (352) 273-7851

Business Email: mark.rogge@ufl.edu

Teaching Profile

Courses Taught

2023-2025

PHA6418 Model-Informed Drug Development

Publications

Academic Articles

2024

Modeling serum M-protein response for early detection of biochemical relapse in myeloma patients treated with bortezomib, lenalidomide and dexamethasone.

CPT: pharmacometrics & systems pharmacology. [DOI] 10.1002/psp4.13225. [PMID] 39287606.

PubMed · Publisher’s Site

2019

Targeting RNA: A Transformative Therapeutic Strategy.

Clinical and translational science. 12(2):98-112 [DOI] 10.1111/cts.12624. [PMID] 30706991.

83 citations · PubMed · Publisher’s Site

2018

A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.

CPT: pharmacometrics & systems pharmacology. 7(9):581-592 [DOI] 10.1002/psp4.12323. [PMID] 30043511.

18 citations · PubMed · Publisher’s Site

2015

Population pharmacokinetics of recombinant factor VIII Fc fusion protein.

Clinical pharmacology in drug development. 4(3):163-74 [DOI] 10.1002/cpdd.167. [PMID] 27140796.

40 citations · PubMed · Publisher’s Site

2012

A novel PEGylated interferon beta-1a for multiple sclerosis: safety, pharmacology, and biology.

Journal of clinical pharmacology. 52(6):798-808 [DOI] 10.1177/0091270011407068. [PMID] 21680782.

90 citations · PubMed · Publisher’s Site

2011

Clinical pharmacokinetics of tonapofylline: evaluation of dose proportionality, oral bioavailability, and gender and food effects in healthy human subjects.

Journal of clinical pharmacology. 51(7):1004-14 [DOI] 10.1177/0091270010377633. [PMID] 20926751.

6 citations · PubMed · Publisher’s Site

2007

Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers.

European journal of clinical pharmacology. 63(7):647-56 [PMID] 17473917.

48 citations · PubMed

2003

Population pharmacokinetic and pharmacodynamic modeling of etanercept using logistic regression analysis.

Clinical pharmacology and therapeutics. 73(4):348-65 [PMID] 12709725.

78 citations · PubMed

2001

Integration of pharmacokinetic and pharmacodynamic studies in the discovery, development, and review of protein therapeutic agents: a conference report.

Clinical pharmacology and therapeutics. 69(6):387-99 [PMID] 11406736.

17 citations · PubMed

Grants

Apr 2021 – Mar 2023

Takeda Research Agreement – Rogge Contract

Role: Co-Project Director/Principal Investigator

Funding: TAKEDA PHARM NORTH AMERICA

Contact Details

Phones:

Business:: (352) 273-7851

Emails:

Business:: mark.rogge@ufl.edu

Addresses:

Business Mailing:: PO Box 100494
GAINESVILLE FL 32610