Research

Dr. Schmittgen’s research interests include cancer therapeutics, exosomes as targeted drug delivery systems and the role of noncoding RNAs in cancer initiation and progression.

Dr. Cicali’s research interests include the development and application of quantitative methods to address clinically relevant questions using model-informed drug discovery and development approaches. He is active in the areas of cardiometabolic diseases, special populations, women’s health, and drug-drug interactions, among others.

Dr. Cristofoletti’s research interests include (patho)physiology-based modeling, in vitro in vivo extrapolation of ADME, biopredictive and microphysiological systems and stem cell technology to quantitatively assess sources of PK and PD variability and inform early stages of drug development.

Dr. De Moraes’ research interests include quantitative pharmacology approaches in the areas of chronic diseases, special populations, pharmacogenetics and drug-drug-interactions. A major emphasis has been on diabetes, obesity and bariatric surgery effect on drug metabolism and elimination.

Dr. He’s research interests include 3D printing and biomaterials, cancer immunotherapy, extracellular Vesicles and exosomes for biological programming and nanodelivery, microfluidic organ on chip and regenerative and precision therapeutics.

Dr. Kim’s research interests include optimizing clinical trial designs using imaging data through modeling and simulation to inform the rational design of disease prevention and treatment strategies.

Dr. Mobley’s research interests include application of instructional design principles to optimize student pharmacist learning and the application of critical thinking and reasoning skills to help develop problem-solving abilities.

Dr. Schmidt’s research interests include the application of quantitative analysis tools to address clinically relevant research questions in the areas of antimicrobial chemotherapy, pediatrics, diabetes, cardiovascular safety and postmenopausal osteoporosis.

Dr. Sharma’s research focuses on the in vivo and in vitro preclinical pharmacokinetic studies of new chemical entities and natural products.

Dr. Song’s research interests include adeno-associated virus, or AAV, vector biology, liver and muscle gene delivery, novel function of alpha 1 antitrypsin, or AAT, AAT deficiency and autoimmune and inflammatory diseases.

Dr. Zhang’s research focuses on developing synthetic nanoplatforms to direct immune cells as “living therapeutics.” To this end, his laboratory integrates materials science, immunology, synthetic biology and translational medicine to create novel nanotherapeutics for controlled modulation of the immune system.